You don't actually say if this customer wants to drive more than one set of 'speakers at the same time, but I shall assume that is so.
I would like to make the following observations.
If all of the 'speakers are driven from one amplifier, if the number of 'speakers is changed, e.g. switching a set on or off in one room, then the volume in the other rooms will change.
The total power which the amplifer delivers at any particular volume setting will be divided between all the connected the 'speakers.
If you connect 'speakers in series or in parallel, or in a series/parallel combination, across an amplifier's output, the amplifer will no longer be properly able to damp the 'speakers. It will work, but it certainly won't be "hi-fi". But I suspect that this is of no consequence.
Ceiling 'speakers will not deliver "hi-fi", but again, I suspect that this is of no consequence.
Unless you can acquire an amplifier, or system, specifically designed to drive 4 or more sets of 'speakers, the simplest way to get predictable results might be to use one amplifier for each room and driving only that room's 'speakers, and drive three of the amplifers from an auxilliary output on the fourth.