I have no issues with two phases, but I always fix a notice about the sources of supply being in two different 'main' DB's when they meet in a fitting. It's the same as orange wiring being used in a control panel to indicate an externally-fed circuit that the local main switch won't isolate. This situation does exist in large banks of switches in industrial locations but not normally a humble 2-way at the bottom of a stairwell - it's a different situation to two circuits from the same DB which is quite normal.
First, as the OP says, someone working on the switch might thinkg a lockout on the DB main switch would solve any possibility of either circuit being energised, and then be foiled when someone turns the other DB on. But more insidious is what happens if the two sides became interconnected, when neither section of the installation could be isolated by its main switch. You would only test insulation with respect to circuits in the local board, so if the other board were off the test would not reveal the problem. Then it would be backfed and everything live, but non-operational due to the neutral being isolated.
We would all prefer that only competent sparks changed accessories but we also know that most handy folks feel competent to do a like-for-like swap of a broken switch. A warning sign would help alert them to the consequences of getting things muddled up in this particular switch.