IMHO where you put the notches and holes is building regs,
Where you run cables is wiring regs.
Yesterday's cables are "selected and erected" to yesterday's wiring regs.
When you select and erect it has to be to BS7671:2011. In this case 522.6.100.
That means just because there's a convenient hole in the joist doesn't mean that you can use it for twin&earth, unless of course you fulfil one of the conditions for mechanical protection. I don't have sufficient wisdom to assert whether a notch plate is sufficient protection.
Interestingly the 50mm is from the top or bottom of the joist not the surface of the floor or ceiling, i.e. does not include the depth of the floorboard. Strange.
Laurie